Reinventing Ourselves: A New Look at Microdosing
- 55pluswellness
- Mar 24
- 6 min read
AMANDA GEDEON
You’re reading a preview of the March/April 2025 issue of 55+ Wellness Magazine. For the full version, packed with even more insights, inspiration, and exclusive content, visit MA25

At any stage of life, we hold the power to reinvent ourselves. The human brain is an extraordinary machine, constantly working to reduce the uncertainty of the world around us. From the moment we are born, it begins gathering information about the people we meet, the experiences we have, and the world we encounter through all our senses. It then creates predictions based on these experiences, guiding us through life. This process, called predictive coding, forms the foundation of our Default Mode Network (DMN)—the seat of our ego, and effectively, our personal "operating system."
As we grow older, our brains become more efficient at processing information, helping us adapt to new situations and survive. However, this efficiency often comes at a cost: it can make our thinking more rigid. The beliefs we've formed through years of experience can become so ingrained they limit our ability to see things from different perspectives. This rigidity can impact our relationships, our mental well-being, and even our overall sense of happiness. Family conflicts, missed opportunities, unspoken words, and unfulfilled dreams are just a few examples of how these limitations can hold us back.
But what if there was a way to break free from these constraints, to see the world with fresh eyes and rediscover a sense of possibility? This is where microdosing comes in.
WHAT IS MICRODOSING?
Microdosing is the practice of taking a very small, "sub-hallucinogenic" amount of a psychedelic substance—typically around 5–10% of what is considered a hallucinogenic dose. According to The Microdosing Institute, this practice can enhance creativity, focus, mood, general well being and overall life satisfaction.
Microdosing can be done with various psychedelic substances, such as psilocybin (found in certain mushrooms), LSD, ayahuasca, and mescaline. While access and legality vary, psilocybin is one of the most commonly used substances. It is naturally occurring, and in places like Spain, consumption and possession is legal, although sale and distribution remain regulated.
Unlike full doses of psychedelics, microdosing doesn't cause visual effects or distortions of reality. Instead, microdosers often report subtle changes—such as increased mental clarity, better mood and a heightened sense of connection to the present moment. The beauty of microdosing is that it integrates seamlessly into your daily life. You can still go about your usual activities—work, exercise, socializing, driving—while experiencing these subtle benefits.
HOW DOES PSILOCYBIN WORK?
Psilocybin works by interacting with serotonin receptors in the brain, particularly the 5-HT2a receptors. This interaction helps reduce the activity of the DMN, the part of the brain responsible for maintaining our sense of self and personal beliefs. When the DMN becomes less active, the brain’s thinking patterns become more flexible, allowing for new perspectives and opportunities.
As we age, maintaining mental agility and cognitive health becomes a priority. Our brain’s ability to form new connections (neuroplasticity) slows down with age. Microdosing supports neuroplasticity by loosening the rigid thinking patterns that develop over time. It promotes a more open, flexible mindset, helping to keep our minds sharp, creative, and adaptable.
Whatever our age or challenges, this could mean improved focus, better memory, and a greater ability to navigate life’s challenges with a clear and open mind.

THE BENEFITS OF MICRODOSING: ADDRESSING MENTAL HEALTH AND EMOTIONAL WELL-BEING
Medical studies, including research by Johns Hopkins University, have shown that psilocybin can significantly reduce anxiety, depression, and even certain neurological conditions, particularly in older adults. This research suggests that psilocybin may help improve mental health and emotional well-being in people facing end-of-life concerns, PTSD, dementia, and other challenges.
Dementia: There is growing evidence that psilocybin and other psychedelics may have a positive effect on individuals living with dementia, particularly Alzheimer’s disease. Studies are investigating how psychedelics can help alleviate some of the emotional distress and agitation associated with dementia, promoting a sense of well-being and clarity. While more research is needed, early results show that psilocybin might help ease the emotional and cognitive burden that dementia brings, even providing moments of lucidity and emotional connection for both patients and caregivers.
Obsessive-Compulsive Disorder (OCD): Traditional treatments for OCD, such as therapy and medication, don’t work for everyone, and the repetitive thought patterns can be difficult to break. Psilocybin, through its action on serotonin receptors, has been shown to help “reset” the brain’s neural circuits, potentially disrupting the persistent, repetitive thought patterns seen in OCD.
Post-Traumatic Stress Disorder (PTSD): For those dealing with the aftermath of trauma, PTSD can be deeply debilitating, affecting emotional health, relationships, and overall quality of life. By reducing the hyperactivity of the DMN, microdosing may help individuals “reframe” their trauma, allowing them to process it in a new way. In clinical trials, psilocybin has helped some individuals overcome deeply ingrained trauma, providing relief from nightmares, flashbacks, and emotional numbing. Microdosing offers a potential avenue for emotional healing.

We all know people who face significant mental health challenges, from depression and anxiety to loneliness and existential concerns. As we move into later stages of life, these emotional hurdles can become more pronounced, especially when facing retirement, loss of loved ones or dealing with life transitions.
Research has shown that microdosing can significantly reduce these challenges. The benefits are particularly relevant to older adults looking for ways to improve their emotional health without resorting to prescription medication or intensive therapy. For those dealing with loneliness or grief, microdosing has the potential to reconnect us with a sense of purpose and joy, helping us see life’s possibilities with renewed perspective.
MICRODOSING: A PRACTICAL APPROACH FOR OLDER ADULTS
One of the most appealing aspects of microdosing is its adaptability to different lifestyles. It’s important to know that microdosing doesn’t require any change to your routine, it can be integrated smoothly into your day-to-day activities—whether that’s working, golfing, exercising, trading or enjoying time with family and friends.
Dr. James Fadiman, a pioneering transpersonal psychologist known as "the father of microdosing," has spent decades researching the effects of small doses of psychedelics. His work, which began after the discoveries of Dr. Albert Hofmann (who famously synthesized LSD), has shown that microdosing can promote a sense of well-being, improve creativity, and even help individuals break free from negative habits.
According to Fadiman, microdosing helps "reconnect" the body and mind, improving relationships with both. Many people report benefits such as better sleep, healthier eating habits, clearer thinking, increased energy, and even the resolution of long-standing emotional issues or addictions.
THE PERSONALIZED APPROACH TO MICRODOSING
Microdosing isn’t a one-size-fits-all practice. It requires careful calibration as the optimal dose can vary from person to person. Dosage is based on how the substance interacts with your nervous system, which is influenced by a variety of factors, both internal and external.
Microdosing is typically practiced over a period of six to ten weeks, following a structured protocol. It works best when guided by a qualified facilitator—a role I’m proud to fill. As a certified microdosing facilitator and transpersonal psychology coach, I’ve witnessed firsthand how this practice can bring about profound change, both personally and professionally. Microdosing helped me find clarity in my own life, and I’m passionate about helping others do the same.
SAFETY NOTICE: INTEGRATING MICRODOSING SAFELY
It’s important to note I am not recommending the use of illegal substances. I also want to stress that microdosing may not be suitable for everyone. There are specific health conditions that may not be compatible with this practice, which is why an initial free consultation is essential. Some people find that microdosing can complement their existing treatment plans, helping them feel more balanced and present. Others may need to adjust their medications to ensure there are no negative interactions. I work closely with medical professionals, including a registered doctor and psychologist, to ensure a responsible and ethical approach to microdosing. Your safety and well-being are my top priority.
If this article resonates with you, I invite you to reach out. I offer 1 to 1 consultations tailored to your health and personal goals. Feel free to contact me at transpersonalmicrodosing@gmail.com or (+34) 695153139.
FURTHER READING
You’re reading a preview of the March/April 2025 issue of 55+ Wellness Magazine. For the full version, packed with even more insights, inspiration, and exclusive content, visit MA25